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COLURACETAM(MKC-231)

CAS # : 135463-81-9

Prduct Price: Contact us to get the latest price

Product Specification : 98%

Minmum Order Quantity : >50g

Sample Requirement : Free Sample / Freight Charged / to final agreement

Product Introduction

What is Coluracetam (MKC-231)?


Coluracetam (MKC-231) is a synthetic Racetam drug purported to be a Nootropic compound. It does not have a large body of evidence investigating it, but the mechanisms of action (as well as structute) appear to be very distinct from other racetam compounds like Piracetam or Aniracetam.


How Coluracetam (MKC-231) works ?


Coluracetam appears to interact with a process known as high affinity choline uptake (HACU for short), which is the rate-limiting step of drawing choline into a neuron for synthesis into the neurotransmitter acetylcholine. Increasing the HACU rate appears to increase the activity of cholinergic neurons, so it is a desired target for cognitive enhancement.

Coluracetam has a lot of characteristics in common with other Racetams, but there are also some important distinctions. It is thought to work by increasing Choline uptake into neurons, even if they are already impaired or damaged. Some evidence suggests that Coluracetam might be particularly effective in the areas of the brain involved in visual processing.


Dosages and Suggestion


Suggested doses for supplement use are based on rat studies and thus were recommended to be between 2.5 – 3 mg/kg orally.

In the patent for coluracetam as treatment for depression and anxiety, the dose used ranged from 80 mg orally once to three times daily.

Coluracetam is commonly dosed from 50-150 mg with most nootropic users.

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