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NSI-189

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Product Specification : 98%

Minmum Order Quantity : >50g

Sample Requirement : Free Sample / Freight Charged / to final agreement

Product Introduction

What is NSI-189 ?


NSI-189 is neurogenic and nootropic research agent that was developed from nicotinamide and pyrazine. Randomized controlled trials have shown that it stimulates neurogenesis or neuronal cell production in the brain. In animal studies, it has also been shown to increase the volume of hippocampus by 20% thereby reversing behavioral symptoms of depression. Such studies have shown that it may be an effective treatment for depression. It is also thought to be a promising treatment for other condition including post-traumatic stress disorder (PTSD), Alzheimer’s disease and age-related cognitive problems.

NSI-189 has been proved that is thought to potentially promote increased neuronal production whilst treat depression is NSI-189. This article discusses NSI-189 and how this novel nootropic agent can revolutionize the treatment for depression, and possibly other neurodegenerative disorders.

Current treatments for major depressive disorder (MDD) mostly include the use of oral medications to modulate critical neurotransmitters in the brain. Selective serotonin reuptake inhibitors (SSRIs) are believed to be the most commonly and widely prescribed treatment for depression. Most recent research however reveals that there is a new theory regarding the cause of major depressive disorder. This theory implicates that brain physiology also influences depression rather than brain chemistry problems alone. Researchers have discovered that the disease leads to decreased hippocampal volume. Note that a healthy hippocampus is an excellent source of neural stem cells which lead to the production of neurons. Neurons on the other hand are critical for creating essential new connections in the brain. Through the production of new neurons in the hippocampal area, depression can be treated.



How NSI-189 works ?


This drug was developed to address three important aspects of depression including hippocampal volume, neurogenesis and neurotransmission. NSI-189 increases the volume within the hippocampus. In so doing, hippocampal volume and healthy brain cell density is increased thereby improving mod and cognitive performance.  Aside from increasing hippocampal volume, the drug also improves neuronal cell functionality. It works it promoting healthy neuronal cell growth whilst repair damaged areas in the brain.


Dosage and Suggestion ?


Studies conducted to evaluate effects of NSI-189 revealed that 40 to 80 mg daily is effective in treating depression and cognitive symptoms amongst healthy patients. In these trials, there are no serious adverse events recorded. Generally, NSI-189 is well tolerated and safe for human use.



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