Agmatine sulfate is a bodybuilding supplement that has gained its popularity over the years through its numerous benefits in building muscle,losing fat and increase in performance.although it is largely found in pre-workouts due to nitric oxide production when the timing of agmatine supplementation is changed to post workout,it can greatly improve your recovery.this is why we have decided to include agmatine as one of our 8 ingredients in our intra+post workout supplement: Myocore
What is Agmatine Sulfate ?
Agmatine sulfate, also known as 1-(4-Aminobutyl)guanidine,is naturally derived from a chemical called arginine,it is an ingredient frequently found in a wide range of bodybuilding supplements from pre-workout to post-workout like our intra+ post workout supplement:Myocore.Research shows it benefits heart,muscle,and brain health,and facilitates the production of nitric oxide for healthy circulation.
What is Agmatine sulfate used for ?
Agmatine sulfate,in recent years,the amino acid arginine has been used in various forms to promote increased blood flow and vasculary through the production of nitric oxide
When should i take Agmatine sulfate ?
Agmatine can be taken in multiple scenarios .due to its ability to produce nitric oxide,supplement with agmatine sulfate 20-30 minutes pre workout
what does Agmatine do for the body ?
Agmatine is a well known neurotransmitter,it also works as a neuromodulator in certain processes in the body.current research shows that agmatine has the potential to be used to treat drug addiction and reduce neuropathic pain,it can also protect the brain from the effect of toxins.
Benefits of Agmatine Sulfate supplementation
Increased blood flow (pump);
Promote muscle growth;
Improve weight loss and prevent weight gain;
Improve insulin sensitivity and reduce blood sugar;
Reduction in pain;
Help with depression and anxiety;
Is Agmatine safe ?
A 5 year long case study done on the effect of daily high dosage of agmatine supplements found evidence that it is safe to consume orally.
Side Effects of Agmatine sulfate
There are very minor effects of agmatine sulfate,with a very small percentage of people reporting nausea,diarhea and vomiting.all side effects were cleared after a couple days of discontinued use of agmatine.
Long Overview
While the exact pathways of Agmatine's mechanism of action is still under investigation,studies have shown agmatine's involvements in diabetes,neuroprotection and psychiatric conditions.
References
Fairbanks, C. A., Schreiber, K. L., Brewer, K. L., Yu, C. G., Stone, L. S., Kitto, K. F., . . . Wilcox, G. L. (2000, September 12). Agmatine reverses pain induced by inflammation, neuropathy, and spinal cord injury. Retrieved from https://www.ncbi.nlm.nih.gov/pmc/articles/PMC27068/Gilad, G. M., & Gilad, V. H. (2014, November). Long-term (5 years), high daily dosage of dietary agmatine--evidence of safety: A case report. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/25247837Kalra, S. P., Pearson, E., Sahu, A., & Kalra, P. S. (1995, July 21). Agmatine, a novel hypothalamic amine, stimulates pituitary luteinizing hormone release in vivo and hypothalamic luteinizing hormone-releasing hormone release in vitro. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/7478229Kang, S., Kim, C., Jung, H., Kim, E., Song, H., & Lee, J. E. (2017, February). Agmatine ameliorates type 2 diabetes induced-Alzheimer's disease-like alterations in high-fat diet-fed mice via reactivation of blunted insulin signalling. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/27810390Morrissey, J. J., & Klahr, S. (1997, January). Agmatine activation of nitric oxide synthase in endothelial cells. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/9010916Nissim, I., Horyn, O., Daikhin, Y., Chen, P., Li, C., Wehrli, S. L., . . . Yudkoff, M. (2014, April 04). The molecular and metabolic influence of long term agmatine consumption. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/24523404Shopsin, B. (2013, April). The clinical antidepressant effect of exogenous agmatine is not reversed by parachlorophenylalanine: A pilot study. Retrieved from https://www.ncbi.nlm.nih.gov/pubmed/25287313